Primary structure of the herpesvirus saimiri genome

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Mapping of RNA transcribed from a region of the Herpesvirus saimiri genome required for oncogenicity.

A region of the Herpesvirus saimiri genome that is not essential for replication of the virus has recently been shown to be required for its oncogenicity in New World primates. We have examined the RNAs derived from this region of the genome in permissively infected cells. Two polyadenylated RNAs, of 4.9 and 2.3 kilobases, were the major species coded for by this region of the genome. These two...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 1992

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.66.8.5047-5058.1992